| MSOA Code | MSOA Name | Last 7 Days Cases | Population |
|---|---|---|---|
| E02003579 | Woolston | 105 | 9092 |
| E02003577 | Central Southampton East | 90 | 14201 |
| E02003559 | Upper Shirley | 85 | 7834 |
| E02003550 | Aldermoor & Lordswood | 83 | 7737 |
| E02003567 | Regents Park & Millbrook East | 81 | 7675 |
| E02003563 | Shirley South | 75 | 7820 |
| E02003574 | Sholing East | 73 | 7337 |
| E02003564 | Bitterne East | 72 | 7670 |
| E02003569 | Freemantle | 72 | 8011 |
| E02003568 | Banister Park & Howard Road | 72 | 8997 |
| E02003576 | Itchen | 72 | 8131 |
| E02003555 | Maybush | 71 | 8175 |
| E02003578 | Sholing West | 70 | 6066 |
| E02003562 | Bitterne West | 67 | 8491 |
| E02003552 | Coxford & Lords Hill | 67 | 5985 |
| E02003558 | Shirley Warren | 66 | 7052 |
| E02003554 | Hollybrook | 63 | 6236 |
| E02003572 | Bitterne South | 63 | 6100 |
| E02003570 | Newtown & Nicholstown | 61 | 12217 |
| E02003549 | Bassett Green | 59 | 8999 |
| E02003565 | Bevois Town | 58 | 7518 |
| E02003560 | Redbridge & Millbrook West | 58 | 7436 |
| E02003557 | Highfield & University | 55 | 7125 |
| E02003556 | Townhill Park | 53 | 5834 |
| E02003573 | Thornhill | 51 | 7536 |
| E02003566 | Harefield | 50 | 6089 |
| E02003561 | St Denys | 46 | 8583 |
| E02003571 | Central Southampton West | 45 | 11109 |
| E02003575 | Hightown | 44 | 6585 |
| E02003580 | Weston | 44 | 6003 |
| E02003553 | Swaythling | 42 | 7912 |
| E02003551 | Stoneham | 41 | 6964 |